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According to the
FDA:
"In common
terms, an adverse drug experience (ADE) is either an undesired
side effect, or the lack of a desired effect. The Center for
Veterinary Medicine (CVM) defines an ADE as 'any side effect,
injury, toxicity, or sensitivity reaction (or failure to perform
as expected) associated with use of an animal drug, whether
or not determined to be attributable to the drug.' "
(This means that you need only SUSPECT that the side effect
is caused by the drug; you do not have to prove it.)
|
Carprofen
(Chewables & Tablets) |
The
top ten symptoms of Adverse Reaction Events reported
to the FDA 'possibly' related to oral Carprofen |
October
1, 2004 |
Treated:
12919 |
Reacted:
12516 |
Deaths:
2349 |
Symptom |
Number |
Percentage |
Vomiting |
3428 |
27 |
| ALK PHOS HI, BLD |
2969 |
24 |
| SGPT/ALT HI, BLD |
2957 |
24 |
| Anorexia |
2879 |
23 |
| Depression/Lethargy |
2172 |
17 |
| Bilirubin(TOT) HI, BLD |
1449 |
12 |
| DIARRHEA |
1174 |
9 |
| BUN
HI, BLD |
1033 |
8 |
| CREATININE HI, BLD |
884 |
7 |
| ICTERUS, BODY |
870 |
7 |
| ANEMIA |
828 |
7 |
| LIVER ENZYMES HI, BLD |
765 |
6 |
| SGOT/AST HI, BLD |
751 |
6 |
| CONVULSION(S) |
662 |
5 |
| WBC HI, BLD |
621 |
5 |
|
Deracoxib
(Chewables)
The top ten symptoms of
Adverse Reaction Events reported to the FDA 'possibly'
related to Deracoxib
|
October
1, 2004 |
Treated: 2107 |
Reacted: 2085 |
Deaths: 440 |
Symptom |
Number |
Percentage |
Vomiting |
748 |
36 |
| Anorexia |
464 |
22 |
| ALK PHOS HI, BLD |
378 |
18 |
| Depression/Lethargy |
368 |
18 |
| BUN HI, BLD |
363 |
17 |
| Creatinine Hi, Bld |
310 |
15 |
| SGPT/ALT Hi, Bld |
304 |
15 |
| Diarrhea |
277 |
13 |
| INTERACTION, DRUG(S) |
199 |
10 |
| ANEMIA |
179 |
9 |
| WBC HI, BLD |
168 |
8 |
| ALBUMIN LO, BLD |
155 |
7 |
| P HI, BLD |
148 |
7 |
| DIARRHEA, BLOODY |
117 |
6 |
| MELENA |
117 |
6 |
|
The
top ten symptoms of Adverse Reaction Events reported
to the FDA 'possibly' related to injectable Carprofen
|
| October
1 , 2004 |
Treated:
141 |
Reacted:
141 |
Deaths:
27 |
Symptom |
Number |
Percentage |
Vomiting |
34 |
24 |
| DEPRESSION/LETHARGY |
24 |
17 |
| Anorexia |
19 |
13 |
| SGPT/ALT HI, BLD |
18 |
13 |
| ALK PHOS HI, BLD |
16 |
11 |
| INJ SITE SWELLING |
15 |
11 |
| NERVOUSNESS |
15 |
11 |
| DISTRESS |
14 |
10 |
| INJ SITE NECROSIS |
14 |
10 |
| VOCALIZATION |
13 |
9 |
|
The
top ten symptoms of Adverse Reaction Events reported
to the FDA 'possibly' related to oral meloxicam
|
| October
1 , 2004 |
Treated:
416 |
Reacted:416 |
Deaths:45 |
Symptom |
Number |
Percentage |
Vomiting |
104 |
25 |
| Anorexia |
86 |
21 |
| Depression/Lethargy |
76 |
18 |
| Diarrhea |
50 |
12 |
| CREATININE HI, BLD |
32 |
8 |
| ALK PHOS HI, BLD |
31 |
7 |
| BUN HI, BLD |
31 |
7 |
| CONVULSION(S) |
28 |
7 |
| SGPT/ALT HI, BLD |
24 |
6 |
| MELENA |
23 |
6 |
|
The
top ten symptoms of Adverse Reaction Events reported
to the FDA 'possibly' related to oral tepoxalin
|
| October
1 , 2004 |
Treated:
394 |
Reacted:366 |
Deaths:
51 |
Symptom |
Number |
Percentage |
Vomiting |
91 |
25 |
| Diarrhea |
71 |
19 |
| Anorexia |
41 |
11 |
| Diarrhea, Bloody |
40 |
11 |
| Depression, Lethargy |
37 |
10 |
| INEFFECT, ANTIINFLAM |
25 |
7 |
| Melena |
22 |
6 |
| VOMITING,
BLOODY |
22 |
6 |
| INTERACTION, DRUG(S) |
21 |
6 |
| UNPALATABLE, WON'T SWA |
16 |
4 |
|
The
top ten symptoms of Adverse Reaction Events reported
to the FDA 'possibly' related to oral etodolac
|
| October
1 , 2004 |
Treated:
1720 |
Reacted:
1573 |
Deaths:
158 |
Symptom |
Number |
Percentage |
VOMITING |
305 |
19 |
| DIARRHEA, BLOODY |
281 |
18 |
| ANOREXIA |
252 |
16 |
| DIARRHEA |
230 |
15 |
| KERATOCONJUNCTIVITIS S |
177 |
11 |
| DEPRESSION/LETHARGY |
160 |
10 |
| ALK PHOS HI, BLD |
143 |
9 |
| SGPT/ALT
HI, BLD |
135 |
9 |
| LIVER ENZYMES HI, BLD |
105 |
7 |
| MELENA |
90 |
6 |
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