Part III: Rabies Vaccines Licensed and Marketed in the United States, 2003
| Product Name |
Produced by |
Marketed by |
For use in |
Dosage |
Age at primary vaccinationa |
Booster recommended |
Route of inoculation |
| A) MONOVALENT (Inactivated) |
| TRIMUNE |
Fort Dodge Animal Health License No. 112 |
Fort Dodge Animal Health |
Dogs Cats |
1 mL 1 mL |
3 monthsb 3 months |
1 year later & triennially 1 year later & triennially |
IMc IM |
| DEFENSOR 1 |
Pfizer, Incorporated License No. 189 |
Pfizer, Incorporated |
Dogs Cats |
1 mL 1 mL |
3 months 3 months |
Annually Annually |
IM or SCd SC |
| DEFENSOR 3 |
Pfizer, Incorporated License No. 189 |
Pfizer, Incorporated |
Dogs Cats Sheep Cattle |
1 mL 1 mL 2 mL 2 mL |
3 months 3 months 3 months 3 months |
1 year later & triennially 1 year later & triennially Annually Annually |
IM or SC SC IM IM |
| RABDOMUN |
Pfizer, Incorporated License No. 189 |
Schering-Plough |
Dogs Cats Sheep Cattle |
1 mL 1 mL 2 mL 2 mL |
3 months 3 months 3 months 3 months |
1 year later & triennially 1 year later & triennially Annually Annually |
IM or SC SC IM IM |
| RABDOMUN 1 |
Pfizer, Incorporated License No. 189 |
Schering-Plough |
Dogs Cats |
1 mL 1 mL |
3 months 3 months |
Annually Annually |
IM or SC SC |
| RABVAC 1 |
Fort Dodge Animal Health License No. 112 |
Fort Dodge Animal Health |
Dogs Cats |
1 mL 1 mL |
3 months 3 months |
Annually Annually |
IM or SC IM or SC |
| RABVAC 3 |
Fort Dodge Animal Health License No. 112 |
Fort Dodge Animal Health |
Dogs Cats Horses |
1 mL 1 mL 2 mL |
3 months 3 months 3 months |
1 year later & triennially 1 year later & triennially Annually |
IM or SC IM or SC IM |
| PRORAB-1 |
Intervet, Incorporated License No. 286 |
Intervet, Incorporated |
Dogs Cats Sheep |
1 mL 1 mL 2 mL |
3 months 3 months 3 months |
Annually Annually Annually |
IM or SC IM or SC IM |
| PRORAB-3F |
Intervet, Incorporated License No. 286 |
Intervet, Incorporated |
Cats |
1 mL |
3 months |
1 year later & triennially |
IM or SC |
| IMRAB 3 |
Merial, Incorporated License No. 298 |
Merial, Incorporated |
Dogs Cats Sheep Cattle Horses Ferrets |
1 mL 1 mL 2 mL 2 mL 2 mL 1 mL |
3 months 3 months 3 months 3 months 3 months 3 months |
1 year later & triennially 1 year later & triennially 1 year later & triennially 1 year later & triennially Annually Annually |
IM or SC IM or SC IM or SC IM or SC IM or SC SC |
| IMRAB 3 TF |
Merial, Incorporated License No. 298 |
Merial, Incorporated |
Dogs Cats Ferrets |
1 mL 1 mL 1 mL |
3 months 3 months 3 months |
1 year later & triennially 1 year later & triennially Annually |
IM or SC IM or SC SC |
IMRAB Large Animal |
Merial, Incorporated License No. 298 |
Merial, Incorporated |
Cattle Horses Sheep |
2 mL 2 mL 2 mL |
3 months 3 months 3 months |
Annually Annually 1 year later & triennially |
IM or SC IM or SC IM or SC |
| IMRAB 1 |
Merial, Incorporated License No. 298 |
Merial, Incorporated |
Dogs Cats |
1 mL 1 mL |
3 months 3 months |
Annually Annually |
SC SC |
| B) MONOVALENT (Rabies glycoprotein, live canary pox vector) |
PUREVAX Feline Rabies |
Merial, Incorporated License No. 298 |
Merial, Incorporated |
Cats |
1 mL |
8 weeks |
Annually |
SC |
| C) COMBINATION (Inactivated rabies) |
ECLIPSE 3 + FeLV/R |
Fort Dodge Animal Health License No. 112 |
Schering-Plough |
Cats |
1 mL |
3 months |
Annually |
IM or SC |
ECLIPSE 4 + FeLV/R |
Fort Dodge Animal Health License No. 112 |
Schering-Plough |
Cats |
1 mL |
3 months |
Annually |
IM or SC |
Fel-O-Guard 3 + FeLV/R |
Fort Dodge Animal Health License No. 112 |
Fort Dodge Animal Health |
Cats |
1 mL |
3 months |
Annually |
IM or SC |
Fel-O-Guard 4 + FeLV/R |
Fort Dodge Animal Health License No. 112 |
Fort Dodge Animal Health |
Cats |
1 mL |
3 months |
Annually |
IM or SC |
IMRAB 3 + Feline 3 |
Merial, Incorporated License No. 298 |
Merial, Incorporated |
Cats |
1 mL |
3 months |
1 year later & triennially |
SC |
IMRAB 3 + Feline 4 |
Merial, Incorporated License No. 298 |
Merial, Incorporated |
Cats |
1 mL |
3 months |
1 year later & triennially |
SC |
| MYSTIQUE II |
Intervet, Incorporated License No. 286 |
Intervet, Incorporated |
Horses |
1 mL |
3 months |
Annually |
IM |
EQUINE POTOMAVAC + IMRAB |
Merial, Incorporated License No. 298 |
Merial, Incorporated |
Horses |
1 mL |
3 months |
Annually |
IM |
| D) COMBINATION (Rabies glycoprotein, live canary pox vector) |
PUREVAX Feline 3/ Rabies |
Merial, Incorporated License No. 298 |
Merial, Incorporated |
Cats |
1 mL |
8 weeks |
Annually |
SC |
PUREVAX Feline 4/ Rabies |
Merial, Incorporated License No. 298 |
Merial, Incorporated |
Cats |
1 mL |
8 weeks |
Annually |
SC |
PUREVAX Feline 3/ Rabies + LEUCAT |
Merial, Incorporated License No. 298 |
Merial, Incorporated |
Cats |
1 mL |
8 weeks |
Annually |
SC |
PUREVAX Feline 4/ Rabies + LEUCAT |
Merial, Incorporated License No. 298 |
Merial, Incorporated |
Cats |
1 mL |
8 weeks |
Annually |
SC |
| E) ORAL (Rabies glycoprotein, live vaccinia vector) - RESTRICTED TO USE IN STATE AND FEDERAL RABIES CONTROL PROGRAMS |
| RABORAL V-RG |
Merial, Incorporated License No. 298 |
Merial, Incorporated |
Raccoons Coyotes |
N/A |
N/A |
As determined by local authorities |
Oral |
| a. Minimum age (or older) and revaccinated one year later. b. A month = 28 days. c. Intramuscularly. d. Subcutaneously. |
References
1. Rabies. In: Chin J, ed. Control of communicable diseases manual. 17th ed. Washington, DC: American Public Health Association, 2000:411-419.
2. AVMA House of Delegates. Model rabies control ordinance. In: 2002 Directory and resource manual. Schaumburg, Ill: American Veterinary Medical Association, 2002:114-116.
3. Bunn TO. Canine and feline vaccines, past and present. In: Baer GM, ed. The natural history of rabies. 2nd ed. Boca Raton, Fla: CRC Press Inc, 1991:415-425.
4. Rupprecht CE, Blass L, Smith K, et al. Human infection due to recombinant vaccinia-rabies glycoprotein virus. N Engl J Med 2001;345:582-586.
5. Centers for Disease Control and Prevention (CDC). Human rabies prevention—United States, 1999. Recommendations of the Advisory Committee on Immunization Practices (ACIP). Morb Mortal Wkly Rep 1999;48(RR-1)1-21.
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10. AVMA Executive Board. Position on canine hybrids. In: 2002 Directory and resource manual. Schaumburg, Ill: American Veterinary Medical Association, 2002:88-89.
11. Duman E. Is it a wolf and what will it do?, in Proceedings. Mich Vet Conf 1993;1-3.
12. Siino BS. Crossing the line. ASPCA Animal Watch 2000;winter:22-29.
13. Hanlon CA, Niezgoda MN, Rupprecht CE. Postexposure prophylaxis for prevention of rabies in dogs. Am J Vet Res 2002;63:
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14. Centers for Disease Control and Prevention (CDC). Mass treatment of humans who drank unpasteurized milk from rabid cows—Massachusetts, . Morbid Mortal Wkly Rep 1999;48:228-229.
15. Hanlon CA, Smith JS, Anderson GR, et al. Recommendations of a national working group on prevention and control of rabies in the United States. Article II: laboratory diagnosis of rabies. J Am Vet Med Assoc 1999;215:.
Report of the AVMA Panel on Euthanasia. J Am Vet Med Assoc 2001;218:669-696.
17. Jenkins SR, Perry BD, Winkler WG. Ecology and epidemiology of raccoon rabies. Rev Infect Dis 1988;10(suppl 4):S620-S625.
18. Messenger SL, Smith JS, Rupprecht CE. Emerging epidemiology of bat-associated cryptic cases of rabies in humans in the United States. Clin Infect Dis 2002;35:738-747.
19. Frantz SC, Trimarchi CV. Bats in human dwellings: health concerns and management, in Proceedings. 1st East Wildl Dam Control Conf 1983;299-308.
20. Greenhall AM. House bat management. Resource Publication 143. US Fish and Wildlife Service, 1982.
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