Rabies


 Part III: Rabies Vaccines Licensed and Marketed in the United States, 2003

Product Name Produced by Marketed by For use in Dosage Age at primary vaccinationa Booster recommended Route of inoculation
A) MONOVALENT (Inactivated)
TRIMUNE Fort Dodge Animal Health
License No. 112
Fort Dodge Animal Health Dogs
Cats
1 mL
1 mL
3 monthsb
3 months
1 year later & triennially
1 year later & triennially
IMc
IM
DEFENSOR 1 Pfizer, Incorporated
License No. 189
Pfizer, Incorporated Dogs
Cats
1 mL
1 mL
3 months
3 months
Annually
Annually
IM or SCd
SC
DEFENSOR 3 Pfizer, Incorporated
License No. 189
Pfizer, Incorporated Dogs
Cats
Sheep
Cattle
1 mL
1 mL
2 mL
2 mL
3 months
3 months
3 months
3 months
1 year later & triennially
1 year later & triennially
Annually
Annually
IM or SC
SC
IM
IM
RABDOMUN Pfizer, Incorporated
License No. 189
Schering-Plough Dogs
Cats
Sheep
Cattle
1 mL
1 mL
2 mL
2 mL
3 months
3 months
3 months
3 months
1 year later & triennially
1 year later & triennially
Annually
Annually
IM or SC
SC
IM
IM
RABDOMUN 1 Pfizer, Incorporated
License No. 189
Schering-Plough Dogs
Cats
1 mL
1 mL
3 months
3 months
Annually
Annually
IM or SC
SC
RABVAC 1 Fort Dodge Animal Health
License No. 112
Fort Dodge Animal Health Dogs
Cats
1 mL
1 mL
3 months
3 months
Annually
Annually
IM or SC
IM or SC
RABVAC 3 Fort Dodge Animal Health
License No. 112
Fort Dodge Animal Health Dogs
Cats
Horses
1 mL
1 mL
2 mL
3 months
3 months
3 months
1 year later & triennially
1 year later & triennially
Annually
IM or SC
IM or SC
IM
PRORAB-1 Intervet, Incorporated
License No. 286
Intervet, Incorporated Dogs
Cats
Sheep
1 mL
1 mL
2 mL
3 months
3 months
3 months
Annually
Annually
Annually
IM or SC
IM or SC
IM
PRORAB-3F Intervet, Incorporated
License No. 286
Intervet, Incorporated Cats 1 mL 3 months 1 year later & triennially IM or SC
IMRAB 3 Merial, Incorporated
License No. 298
Merial, Incorporated Dogs
Cats
Sheep
Cattle
Horses
Ferrets
1 mL
1 mL
2 mL
2 mL
2 mL
1 mL
3 months
3 months
3 months
3 months
3 months
3 months
1 year later & triennially
1 year later & triennially
1 year later & triennially
1 year later & triennially
Annually
Annually
IM or SC
IM or SC
IM or SC
IM or SC
IM or SC
SC
IMRAB 3 TF Merial, Incorporated
License No. 298
Merial, Incorporated Dogs
Cats
Ferrets
1 mL
1 mL
1 mL
3 months
3 months
3 months
1 year later & triennially
1 year later & triennially
Annually
IM or SC
IM or SC
SC
IMRAB
Large Animal
Merial, Incorporated
License No. 298
Merial, Incorporated Cattle
Horses
Sheep
2 mL
2 mL
2 mL
3 months
3 months
3 months
Annually
Annually
1 year later & triennially
IM or SC
IM or SC
IM or SC
IMRAB 1 Merial, Incorporated
License No. 298
Merial, Incorporated Dogs
Cats
1 mL
1 mL
3 months
3 months
Annually
Annually
SC
SC
B) MONOVALENT (Rabies glycoprotein, live canary pox vector)
PUREVAX Feline
Rabies
Merial, Incorporated
License No. 298
Merial, Incorporated Cats 1 mL 8 weeks Annually SC
C) COMBINATION (Inactivated rabies)
ECLIPSE 3 +
FeLV/R
Fort Dodge Animal Health
License No. 112
Schering-Plough Cats 1 mL 3 months Annually IM or SC
ECLIPSE 4 +
FeLV/R
Fort Dodge Animal Health
License No. 112
Schering-Plough Cats 1 mL 3 months Annually IM or SC
Fel-O-Guard 3 +
FeLV/R
Fort Dodge Animal Health
License No. 112
Fort Dodge Animal Health Cats 1 mL 3 months Annually IM or SC
Fel-O-Guard 4 +
FeLV/R
Fort Dodge Animal Health
License No. 112
Fort Dodge Animal Health Cats 1 mL 3 months Annually IM or SC
IMRAB 3 +
Feline 3
Merial, Incorporated
License No. 298
Merial, Incorporated Cats 1 mL 3 months 1 year later & triennially SC
IMRAB 3 +
Feline 4
Merial, Incorporated
License No. 298
Merial, Incorporated Cats 1 mL 3 months 1 year later & triennially SC
MYSTIQUE II Intervet, Incorporated
License No. 286
Intervet, Incorporated Horses 1 mL 3 months Annually IM
EQUINE
POTOMAVAC +
IMRAB
Merial, Incorporated
License No. 298
Merial, Incorporated Horses 1 mL 3 months Annually IM
D) COMBINATION (Rabies glycoprotein, live canary pox vector)
PUREVAX Feline 3/
Rabies
Merial, Incorporated
License No. 298
Merial, Incorporated Cats 1 mL 8 weeks Annually SC
PUREVAX Feline 4/
Rabies
Merial, Incorporated
License No. 298
Merial, Incorporated Cats 1 mL 8 weeks Annually SC
PUREVAX Feline 3/
Rabies + LEUCAT
Merial, Incorporated
License No. 298
Merial, Incorporated Cats 1 mL 8 weeks Annually SC
PUREVAX Feline 4/
Rabies + LEUCAT
Merial, Incorporated
License No. 298
Merial, Incorporated Cats 1 mL 8 weeks Annually SC
E) ORAL (Rabies glycoprotein, live vaccinia vector) - RESTRICTED TO USE IN STATE AND FEDERAL RABIES CONTROL PROGRAMS
RABORAL V-RG Merial, Incorporated
License No. 298
Merial, Incorporated Raccoons
Coyotes
N/A N/A As determined by local authorities Oral
a. Minimum age (or older) and revaccinated one year later.   b. A month = 28 days.   c. Intramuscularly.   d. Subcutaneously.


References
1. Rabies. In: Chin J, ed. Control of communicable diseases manual. 17th ed. Washington, DC: American Public Health Association, 2000:411-419.
2. AVMA House of Delegates. Model rabies control ordinance. In: 2002 Directory and resource manual. Schaumburg, Ill: American Veterinary Medical Association, 2002:114-116.
3. Bunn TO. Canine and feline vaccines, past and present. In: Baer GM, ed. The natural history of rabies. 2nd ed. Boca Raton, Fla: CRC Press Inc, 1991:415-425.
4. Rupprecht CE, Blass L, Smith K, et al. Human infection due to recombinant vaccinia-rabies glycoprotein virus. N Engl J Med 2001;345:582-586.
5. Centers for Disease Control and Prevention (CDC). Human rabies prevention—United States, 1999. Recommendations of the Advisory Committee on Immunization Practices (ACIP). Morb Mortal Wkly Rep 1999;48(RR-1)1-21.
6. Krebs JW, Noll HR, Rupprecht CE. Rabies surveillance in the United States during 2001. J Am Vet Med Assoc 2002;221: .
7. Hanlon CA, Childs JE, Nettles VF, et al. Recommendations of a national working group on prevention and control of rabies in the United States. Article III: rabies in wildlife. J Am Vet Med Assoc 1999;215:.
8. Tizard I, Ni Y. Use of serologic testing to assess immune status of companion animals. J Am Vet Med Assoc 1998;213:54-60.
9. AVMA House of Delegates. Wild animals as pets. In: 2002 Directory and resource manual. Schaumburg, Ill: American Veterinary Medical Association, 2002:126.
10. AVMA Executive Board. Position on canine hybrids. In: 2002 Directory and resource manual. Schaumburg, Ill: American Veterinary Medical Association, 2002:88-89.
11. Duman E. Is it a wolf and what will it do?, in Proceedings. Mich Vet Conf 1993;1-3.
12. Siino BS. Crossing the line. ASPCA Animal Watch 2000;winter:22-29.
13. Hanlon CA, Niezgoda MN, Rupprecht CE. Postexposure prophylaxis for prevention of rabies in dogs. Am J Vet Res 2002;63: .
14. Centers for Disease Control and Prevention (CDC). Mass treatment of humans who drank unpasteurized milk from rabid cows—Massachusetts, . Morbid Mortal Wkly Rep 1999;48:228-229.
15. Hanlon CA, Smith JS, Anderson GR, et al. Recommendations of a national working group on prevention and control of rabies in the United States. Article II: laboratory diagnosis of rabies. J Am Vet Med Assoc 1999;215:.
Report of the AVMA Panel on Euthanasia. J Am Vet Med Assoc 2001;218:669-696.
17. Jenkins SR, Perry BD, Winkler WG. Ecology and epidemiology of raccoon rabies. Rev Infect Dis 1988;10(suppl 4):S620-S625.
18. Messenger SL, Smith JS, Rupprecht CE. Emerging epidemiology of bat-associated cryptic cases of rabies in humans in the United States. Clin Infect Dis 2002;35:738-747.
19. Frantz SC, Trimarchi CV. Bats in human dwellings: health concerns and management, in Proceedings. 1st East Wildl Dam Control Conf 1983;299-308.
20. Greenhall AM. House bat management. Resource Publication 143. US Fish and Wildlife Service, 1982.

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